Clinical Pearls

"Clinical Pearls" appeared in Cancer Strategies Journal in issues in 2013 and 2014. Edited by integrative oncologist Dwight McKee, MD, these insights are based on research and clinical practice of Donnie Yance and his colleagues at the Mederi Foundation in Oregon. These "clinical pearls" exemplify the thinking that Dr. McKee has been developing throughout his career. We are grateful to Dr. McKee and to Eve Katz, editor of Cancer Strategies Journal, for permission to make these clinical insights available to BCCT.

Winter 2013

PDF document, 2 pages

  • Progressive muscle relaxation (PMR)
  • Research paper on cancer outcomes flawed
  • Dandelion in cooking
  • Resveratrol ball recipe
  • Bone marrow broth and botanical bone marrow support
  • Suggestions to treat diarrhea from chemotherapy treatments
  • Think of silymarin in non-small-cell lung cancer
  • Galectin-3 levels and citrus pectin

Spring 2013

PDF document, 2 pages

  • Nettles seed and reduced renal function and cancer
  • G6PD deficiency and IV vitamin C
  • Niacinamide and triple negative breast cancer
  • Building platelet counts
  • Lactoferrin helps bone building
  • Cancer and high HbA1c
  • Lumbrokinase for high fibrinogen in cancer
  • Helping patients with non-small-cell lung cancer
    • Coriolus versicolor (turkey tail)
    • Green tea extract
    • Lactoferrin
    • Cachexia with lung cancer
  • DIM In Ovarian Cancer
  • Elevation of cAMP levels by forskolin induces death of multiple myeloma cells

Summer 2013

PDF document, 2 pages

  • Rapamycin
  • Clarithromycin and non-small-cell lung cancer
  • Beta-blockers reduce breast cancer mortality
  • Off-label use of metformin
  • Cimetidine
  • Dipyridamole
  • Do red yeast rice and lovastatin inhibit prostate tumor growth?
  • Statins and colon cancer
  • Amino-bisphosphonates as anticancer agents
  • Artemisinin compounds reasonable to try against cancer
  • HIV protease inhibitor drugs

Fall 2013

PDF document, 2 pages

  • Copper chelation with TM
  • Diet and supplements for her2positive patients on Herceptin
  • Lapatinib in treating her2neu positive cancers
  • Glycine
  • High vitamin D levels in patients with cancer who have high CRP and/or sed rate
  • Botanicals and food changes to make thearpies more effective with squemous cell cancers
  • Insulin-regulating herbs, nutrients, and foods for squamous cell cancers
  • Diet to strengthen lung energy
  • Supplements and natural products as expectorants
  • EEG Biofeedback for reversing or reducing the cognitive sequelae of cancer treatment
  • Glioblastoma multiforme (GBM) and the ketogenic diet
  • Fasting as an adjunct to chemotherapy
  • Herbal formula for treating multiple myeloma

Winter 2014

PDF document, 2 pages

  • Wisconsin ginseng (Panax quinquefolius) to improve cancer-related fatigue
  • Soy food intake and breast cancer
  • TCM formula for multiple myeloma
  • Developing a botanical protocol

Spring 2014

PDF document, 2 pages

  • Adrenal fatigue as a potential differential diagnosis
  • Evaluate small intestinal bacterial overgrowth
  • PHY906 1800-year-old Chinese botanical formula
  • Heparin therapy and cancer patients
  • Lumbrokinase more effective in the cancer setting
  • Concentrated anthocyanins for cancer care

Summer 2014

PDF document, 1 page

  • Bladder cancer pearls
  • Chemotherapy appears to have long-term effects on the brain and possibly other tissues
  • L-carnitine supplementation for fatigue and loss of muscle mass
  • Antioxidants do not interfere with therapeutic modalities for cancer

Fall 2015

PDF document, 2 pages

  • Timing of supplements to reduce nausea
  • Botanical compounds that either activate/up-regulate PTEN and/or inhibit PTEN mutation
  • Botanical compounds that target BCL2
  • Agents targeting HIF-1a (hypoxia inducible factor alpha-1)—response to hypoxia which makes tumor cells more aggressive
  • Uses of vitamin K3
  • Nettles seed and kidneys
  • Egg yolks as material to make liposomal botan¬ical preparations just before consumption
  • Herbal compounds that inhibit mTOR/PI3K (phosphatidylinositol 3-kinase) and suppress cancer

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