Coenzyme Q10

BCCT plans to write a summary on Coenzyme Q10 (CoQ 10). While our summary is in development, you can visit these sites:

Clinical Practice Guidelines

According to the Society for Integrative Oncology’s 2017 clinical practice guidelines for breast cancer, insufficient information exists to recommend using coenzyme Q10 for relieving depression/mood or fatigue or improving quality of life.1

Managing Side Effects and Promoting Wellness

Managing or relieving side effects or symptoms, reducing treatment toxicity, supporting quality of life or promoting general well-being

Co Q10 is used for a variety of symptoms.


According to About Herbs and CAM-Cancer, only minor side effects have been reported. About Herbs cautions that Co Q10 may reduce effectiveness of chemotherapy and radiation therapy. Some integrative oncologists also list cautions:

  • Don't use with radiation therapy, as it may reduce effectiveness2
  • High doses for long periods may elevate liver enzymes and can interact with blood thinners3

BCCT advises using this supplement under medical supervision of a clinician knowledgeable in using this supplement in cancer care.


BCCT does not recommend therapies or doses, but only provides information for patients and providers to consider as part of a complete treatment plan. Patients should discuss therapies with their physicians, as contraindications, interactions and side effects must be evaluated.

Dosage recommendations are available from these sources:

Integrative Plans, Protocols and Medical Systems

For more information about plans and protocols, see our Integrative Plans and Protocols page.
  • Plans, protocols and programs
    • Abrams & Weil integrative medicine approaches:4
      • Provides evidence for cardioprotectant use in acute lymphocytic leukemia, non-Hodgkin lymphoma and various malignancies
    • Alschuler & Gazella complementary approaches5
      • Breast cancer
      • Cervical cancer
      • Melanoma
      • Ovarian cancer
      • Prostate cancer
      • Thyroid cancer
      • Immune-enhancing approach
      • Anti-inflammatory approach
      • Insulin resistance reversal approach
      • Supporting thyroid and adrenal function
      • Decreasing risk of breast and thyroid cancer and melanoma
    • Block program:6
      • Antioxidant support
      • Immune surveillance support
      • Cardioprotectant during Adriamycin® therapy
      • Use with off-label statins to protect muscle cells7
    • McKinney protocols8
      • Treating organ failure triggered by chemotherapy toxicity
      • Breast cancer: improving heart function before Herceptin® treatment
      • Melanoma
      • Myelodysplastic syndrome: prevent liver, kidney and bone marrow toxicity
      • Repairing sun and other UV damage to skin

View All References

More Information

Enter your comments or questions below.

Comments (0)

Allowed tags: <b><i><br>Add a new comment: