Modified Citrus Pectin
Laura Pole, RN, MSN, OCNS, BCCT Senior Researcher
Nancy Hepp, MS, BCCT Project Manager
Last updated November 20, 2020.
Also known by these names
Pectin is a soluble plant fiber found in highest concentrations in apples and the peel and pulp of citrus fruits. Modified citrus pectin (MCP) is an altered form of citrus peel pectin that is reportedly more absorbable in the body. As a result, natural citrus pectin may not have the same effects on cancer as modified citrus pectin.1
Treating the Cancer
Working against cancer growth or spread, improving survival, or working with other treatments or therapies to improve their anticancer action
Lab and Animal Evidence
Modified citrus pectin is “generally regarded as safe” in the US. However, MCP can cause mild side effects as well as some potentially serious interactions with drugs and supplements, including digoxin, lovastatin and tetracycline. MCP may also slow or reduce absorption of some oral drugs.14 Consult with your pharmacist for interactions, and discuss using MCP with your doctor.
Pectin is found in common food sources, and modified citrus pectin is widely available in supplement form.
Although clinical trials have not established an optimal modified citrus pectin dose during or post cancer treatment, suggested dosages are listed in the integrative cancer care protocols, plans and references below. Levels of active ingredients of natural products can vary widely between and even within products. See Quality and Sources of Herbs, Supplements and Other Natural Products.
More information about dosing pectin is available from these sources:
- Moss R. Moss Report on Prostate Cancer. Modified Citrus Pectin.
- Natural Medicines Database (requires purchase)
- Also see the protocols below.
Integrative Programs, Protocols and Medical Systems
|For more information about programs and protocols, see our Integrative Programs and Protocols page.|
- Programs and protocols
- Alschuler & Gazella complementary approaches15
- Block program16
- Tips for diarrhea
- Reduce platelet aggregation (reducing risk for clots)
- Chang strategies17
- McKinney protocols18
Non-cancer Uses of Modified Citrus Pectin
BCCT has not reviewed the effectiveness of this therapy for non-cancer uses.
Note: BCCT has not conducted an independent review of research of modified citrus pectin. This summary draws primarily from Memorial Sloan Kettering Cancer Center About Herbs and Anticancer Fund website.
- Memorial Sloan Kettering Cancer Center. About Herbs: Pectin.
- TRC Natural Medicines. Pectin (subscription is required): in-depth information, ratings of effectiveness and safety and evaluation of specific pectin products
- Consumer Labs: Product Review (subscription required): Modified citrus pectin
- Moss Reports (purchase required): Select from the list of cancers down the left side of the page for a report describing uses of conventional, complementary, alternative and integrative therapies related to that cancer. Ralph Moss is among the most knowledgeable and balanced researchers of integrative cancer therapies. The cost of his Moss Reports is not negligible, but many patients find them of considerable value. Moss is also available for consultations.
- Gurdev Parmar and Tina Kaczor: Textbook of Naturopathic Oncology
- Dwight McKee, MD, editor: Clinical Pearls
- National Cancer Institute at the National Institutes of Health: PDQ® Cancer Information Summaries
- Raymond Chang, MD: Beyond the Magic Bullet: The Anti-Cancer Cocktail
- Neil McKinney, BSc, ND: Naturopathic Oncology, 3rd Edition
- Lise Alschuler, ND, FABNO, and Karolyn Gazella: The Definitive Guide to Cancer, 3rd Edition
- National Cancer Institute: Complementary and Alternative Medicine for Health Professionals
- National Cancer Institute: Office of Cancer Complementary and Alternative Medicine
- Cancer Research UK