Vitamin C

BCCT plans to write a summary on vitamin C. While our summary is in development, you can visit these sites:


The About Herbs and CAM-Cancer summaries of vitamin C list several contraindications, adverse reactions, herb-drug interactions and herb-lab interactions. For instance, in some studies, vitamin C was found to reduce the effectiveness of some chemotherapy drugs. An example of a contraindication is that serious harm can occur using high-dose vitamin C  in people with glucose-6-phosphate dehydrogenase (G6PD) deficiency, an inborn error of metabolism. Read the summaries for more information:

TRC Natural Medicines Database provides an even more extensive listing and discussion of adverse reactions, contraindications, and herb-drug interactions: TRC Natural Medicines: Vitamin C (subscription required)

Neil McKinney, ND lists a number of cautions and contraindications not listed in other sources, such as avoiding megadoses of vitamin C in leukemia, as it can paradoxically increase malignant cell proliferation. He also cautions not to use during the same week as Artemisinin therapy, nor in tumors with high risk of tumor lysis syndrome and hemorrhage.1

BCCT strongly advises that you speak with your oncology physician if you are thinking about or are taking high-dose vitamin C. BCCT also strongly advises that if you use high dose vitamin C, you seek care from a healthcare professional knowledgeable and experienced in administering this treatment to people with cancer.


BCCT does not recommend therapies or doses, but only provides information for patients and providers to consider as part of a complete treatment plan. Patients should discuss therapies with their physicians, as contraindications, interactions and side effects must be evaluated.

Dosage recommendations are available from these sources:

Integrative Programs, Protocols and Medical Systems

For more information about programs and protocols, see our Integrative Programs and Protocols page.
  • Programs and protocols 
    • Alschuler & Gazella complementary approaches2
      • Bladder cancer
      • Cervical cancer
      • Gastric cancer
      • Liver cancer
      • Pancreatic cancer
      • Hormonal balance (inflammatory triggers)
      • Immune enhancement
      • Anti-inflammation
      • Stress reduction
      • Post-operative healing program
      • Treatment recovery program
    • Bastyr University Integrative Oncology Research Center protocol for stage IV breast cancer3
    • Block program4
      • Core diet plan
      • Antioxidant support formula
      • Immune surveillance
      • Coagulation terrain modifier
      • Hyperadapted stress pattern
    • Lemole, Mehta & McKee protocols: whole foods diet5
    • McKinney protocols6
      • Bladder cancer
      • Brain cancer
      • Breast cancer
      • Cervical cancer
      • Gallbladder cancer
      • Head and neck cancer
      • Lung cancer
      • Lymphoma
      • Multiple myeloma
      • Myelodysplastic syndrome
      • Pancreatic cancer
      • Prostate cancer
      • Renal cell cancer
      • Stomach cancer
      • Uterine cancer
      • Bone metastasis
      • Stem cell modulation
      • Natural compound to target cancer growth factors
      • Oral form: general protocol
      • IV form: foundation protocol for naturopathic oncology to support chemotherapy, improve quality of life and cancer cell cytotoxicity
  • Traditional systems

Highlighted Video

Brian Bouch, MD: Integrative Oncology, Part 2

Read more

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