Pomi-T
Key Points
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Pomi-T® is a food supplement capsule containing green tea, pomegranate seed extract, broccoli extract and turmeric. The individual components in Pomi-T are each rich in polyphenols, natural plant-based phytochemicals that are associated with lowering risk for a number of chronic illnesses and are known for anticancer effects.
Treating the Cancer
Working against cancer growth or spread, improving survival, or working with other treatments or therapies to improve their anticancer action
Clinical Evidence
Pomi-T was tested in a double-blind, placebo-controlled, randomized trial involving 199 men with early-stage prostate cancer in active surveillance or watchful waiting. After six months of treatment, the placebo group's prostate-specific antigen (PSA) levels rose by 78.5 percent, while the Pomi-T treatment group's PSA rose by 14.7 percent. Rising PSA levels are a marker of potential cancer activity.1 The researchers concluded that there was a significant short-term favorable effect on PSA in the men taking Pomi-T.2
Components of Pomi-TThe individual ingredients in Pomi-T are all considered to be rich in polyphenols, natural plant-based phytochemicals that are associated with lowering risk for a number of chronic illnesses as well as having anticancer effects, as described in the study of Pomi-T:3 |
Although one small clinical studies snowed significant effects of Pomi-T on PSA levels, it was of short duration (six months), and no impact on cancer incidence, quality of life or mortality was established.4 Pomi-T shows promise, but as yet no clinical evidence of impact on cancer is available..5
Lab and Animal Evidence
Optimizing Your Terrain
Lab and Animal Evidence
Access
Pomi-T is a food supplement and doesn’t require a prescription. It is generally available at retail pharmacies, supplement stores and online.
Cautions
Because Pomi-T doesn’t contain the sugar in pomegranate juice, use is generally appropriate for patients with diabetes.
Safety of Pomi-T in pregnancy hasn’t been established. Safety recommendations for green tea, pomegranate seed extract, broccoli extract and turmeric should be followed.
Side Effects/Adverse Events
Pomi-T was well tolerated in the study, although a few side effects were noted compared to a control:
- More flatulence and loose bowels
- Mild indigestion, which disappeared if Pomi-T was taken with food
Drug Interactions
Pomegranate has the potential to interact with some drugs, such as warfarin, anti-hypertensives or anti-convulsants. For more information on potential drug interactions see Pomi-T website FAQ’s: Does Pomi-T interact with other drugs?
Dosing
BCCT does not recommend therapies or doses, but only provides information for patients and providers to consider as part of a complete treatment plan. Patients should discuss therapies with their physicians, as contraindications, interactions and side effects must be evaluated. Levels of active ingredients of natural products can vary widely between and even within products. See Quality and Sources of Herbs, Supplements and Other Natural Products.
The Pomi-T official website contains a number of tips on dosing as well as improving the absorption and bioavailability of Pomi-T. The UK site also describes an i-Phone app created to help patients calculate their PSA doubling time between two time points. See the Pomi-T FAQ’s page (Q. How can I accurately follow my PSA doubling time?).
Integrative Programs, Protocols and Medical Systems
| For more information about programs and protocols, see our Integrative Programs and Protocols page. |
Pomi-T is not yet listed in any of the protocols or systems that BCCT references, although several of its constituent ingredients are used in protocols.
Commentary
From BCCT staff, January 4, 2018: In a 2013 post, integrative oncologist Dr. Brian Lawenda cautions, “POMI-T is NOT A TREATMENT FOR PROSTATE CANCER. Make sure you have first discussed this with your cancer care team before taking POMI-T as the individual ingredients have the potential to interact with other therapies you may be receiving.”6 Thus, although Pomi-T has been shown to reduce PSA in early stage prostate cancer, no evidence to date indicates it could stand alone as a treatment for prostate cancer.
Non-cancer Uses of Pomi-TBecause all four Pomi-T ingredients have anti-inflammatory properties, a trial is planned to evaluate the effect of Pomi-T on arthritis.7 BCCT has not reviewed the effectiveness of this therapy for non-cancer uses. |
Written by Laura Pole, RN, MSN, OCNS, and Nancy Hepp, MS; most recent update on May 13, 2019. Note: BCCT has not conducted an independent review of research of Pomi-T. We have drawn from the following sources to create this summary:
- National Cancer Institute: Prostate Cancer, Nutrition, and Dietary Supplements (PDQ®)–Health Professional Version
- Green Med Info: Pomegranate-Polyphenol Food Blend Reduces Prostate PSA Rise
- Pomi-T website: Product
- TRC Natural Medicines: Pomi-T
More Information
- National Cancer Institute: Prostate Cancer, Nutrition, and Dietary Supplements (PDQ®)–Health Professional Version
- Green Med Info: Pomegranate-Polyphenol Food Blend Reduces Prostate PSA Rise
- Pomi-T website: Frequently Asked Questions
- TRC Natural Medicines: Pomi-T (subscription required): in-depth information, ratings of effectiveness and safety and evaluation of specific products
- National Cancer Institute at the National Institutes of Health: PDQ® Cancer Information Summaries
- Cell Nutritionals: Cell Nutritionals: Pomi-T Study
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Comments (2)
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Nancy Hepp:
May 13, 2020 at 10:31 PM
This is from the POMI-T website FAQ (https://www.pomi-t.com/faq/) "Even if all the ingredients are fully certified by our suppliers, we (on our own initiative) re-analyse all batches in order to ensure that commonly-used pesticides, heavy metals and aflatoxins are absent or significantly below the permitted levels." This is not the same as certified organic.
Pok Yang Hang:
May 13, 2020 at 06:27 PM
Are the 4 polyphenols in POMI-T derived from organic sources?